A Multicenter, Randomized, Open-label, Parallel-controlled Phase III Study Comparing the Efficacy and Safety of HRS9531 Injection Versus Semaglutide Injection in Subjects With Obesity
HRS9531, a weekly injectable from Chinese sponsor Fujian Shengdi, is being tested head-to-head against semaglutide in 572 adults with obesity. This 52-week, open-label phase 3 trial completed enrollment and measures percentage weight change as the primary endpoint. The study represents another Chinese GLP-1 biosimilar or follow-on entering direct competition with Novo Nordisk's established semaglutide franchise in obesity. This adds to multiple Chinese developers pursuing GLP-1 programs, potentially targeting domestic and emerging markets where branded pricing creates access gaps.